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Compound Detail

CHEMBL1505690

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Cc1ccc(NC(=O)C(c2ccc(Cl)cc2)N2CCOCC2)cc1

Basic Information

ChEMBL ID CHEMBL1505690
Phase Preclinical
Structure Type MOL
InChI Key IDTDOIBQZXCQIN-UHFFFAOYSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

344.8
MW (Da)
3.66
ALogP
3
HBA
1
HBD
41.6
PSA (Ų)
0.92
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C19H21ClN2O2
MW 344.84
Aromatic Rings 2
Heavy Atoms 24
NP-Likeness -1.81

Activity Summary

EC50 2 meas. best 5.82

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Beta-2 adrenergic receptor
CHEMBL210
EC50 5.82 5.74 1510.0 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine