Compound Detail
CHEMBL150650
SULFAMIC ACID METHYL ESTER Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL150650 |
| Name | SULFAMIC ACID METHYL ESTER |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FIYXUOWXHWJDAM-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
111.1
MW (Da)
-1.16
ALogP
3
HBA
1
HBD
69.4
PSA (Ų)
0.46
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 5.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Carbonic anhydrase 2 CHEMBL205 | Ki | 5.22 | 5.22 | 6000.0 | 1 |
| Carbonic anhydrase 1 CHEMBL261 | Ki | 4.4 | 4.4 | 40000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Carbonic anhydrase 2 | Ki | = | 6000.0 | nM | 5.22 | Inhibitory activity against human carbonic anhydrase II. | 14640555 |
| Carbonic anhydrase 1 | Ki | = | 40000.0 | nM | 4.4 | Inhibitory activity against human carbonic anhydrase I. | 14640555 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14640555 | 10.1021/jm030911u | Carbonic anhydrase 1 | 1 |
| 14640555 | 10.1021/jm030911u | Carbonic anhydrase 2 | 1 |
| 14640555 | 10.1021/jm030911u | Carbonic anhydrase 9 | 1 |
| - | 10.1039/C2MD20079A | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine