Compound Detail
CHEMBL1541803
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1541803 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YSGCOZBFQCLQTM-UHFFFAOYSA-N |
4
Targets
4
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
332.8
MW (Da)
1.82
ALogP
3
HBA
1
HBD
66.5
PSA (Ų)
0.86
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 4.61
IC50 2 meas. best 5.11
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Female germline-specific tumor suppressor gld-1 CHEMBL1293302 | IC50 | 5.11 | 5.11 | 7718.0 | 1 |
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 4.61 | 4.61 | 24678.0 | 1 |
| Protein Rev CHEMBL1293282 | IC50 | 4.59 | 4.59 | 25752.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 4.47 | 4.47 | 34144.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Female germline-specific tumor suppressor gld-1 | IC50 | = | 7718.0 | nM | 5.11 | PUBCHEM_BIOASSAY: Fluorescence polarization-based biochemical high throughput do... | - |
| Zinc finger protein mex-5 | EC50 | = | 24678.0 | nM | 4.61 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| Protein Rev | IC50 | = | 25752.0 | nM | 4.59 | PUBCHEM_BIOASSAY: Counterscreen for inhibitors of gld-1: Fluorescence polarizati... | - |
| RNA-binding protein pos-1 | EC50 | = | 34144.0 | nM | 4.47 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
Data from ChEMBL 36 via Core Engine