Compound Detail
CHEMBL1569232
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1569232 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FIXGNCWNTHTYMQ-UHFFFAOYSA-N |
4
Targets
4
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
316.3
MW (Da)
4.24
ALogP
5
HBA
1
HBD
68.3
PSA (Ų)
0.54
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 6.76
IC50 1 meas. best 4.62
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 6.76 | 6.76 | 173.0 | 1 |
| Unchecked CHEMBL612545 | EC50 | 4.75 | 4.75 | 17950.0 | 1 |
| Mitogen-activated protein kinase 10 CHEMBL2637 | IC50 | 4.62 | 4.62 | 23960.0 | 1 |
| Peroxisome proliferator-activated receptor gamma/Nuclear receptor coactivator 2 CHEMBL2095163 | EC50 | 4.61 | 4.61 | 24320.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RNA-binding protein pos-1 | EC50 | = | 173.0 | nM | 6.76 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| Unchecked | EC50 | = | 17950.0 | nM | 4.75 | PUBCHEM_BIOASSAY: A cytotoxicity screen of small molecule inhibitors of the PhoP... | - |
| Mitogen-activated protein kinase 10 | IC50 | = | 23960.0 | nM | 4.62 | PUBCHEM_BIOASSAY: Dose response biochemical screening assay for inhibitors of c-... | - |
| Peroxisome proliferator-activated receptor gamma/Nuclear receptor coactivator 2 | EC50 | = | 24320.0 | nM | 4.61 | PUBCHEM_BIOASSAY: TR-FRET dose response biochemical High Throughput Screening as... | - |
Data from ChEMBL 36 via Core Engine