Compound Detail
CHEMBL1576762
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Basic Information
| ChEMBL ID | CHEMBL1576762 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DXJLGVQOSRWIHI-UHFFFAOYSA-N |
5
Targets
5
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
388.5
MW (Da)
4.36
ALogP
4
HBA
1
HBD
69.3
PSA (Ų)
0.66
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 5.76
IC50 2 meas. best 4.81
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 5.76 | 5.76 | 1723.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 5.16 | 5.16 | 6939.0 | 1 |
| Unchecked CHEMBL612545 | EC50 | 5.04 | 5.04 | 9130.0 | 1 |
| Beta Lactamase CHEMBL1293246 | IC50 | 4.81 | 4.81 | 15509.0 | 1 |
| Beta-lactamase CHEMBL1293260 | IC50 | 4.56 | 4.56 | 27823.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Zinc finger protein mex-5 | EC50 | = | 1723.0 | nM | 5.76 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| RNA-binding protein pos-1 | EC50 | = | 6939.0 | nM | 5.16 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| Unchecked | EC50 | = | 9130.0 | nM | 5.04 | PUBCHEM_BIOASSAY: HCS for Compounds that Up-Regulate Insulin Promoter Activity i... | - |
| Beta Lactamase | IC50 | = | 15509.0 | nM | 4.81 | PubChem BioAssay. Epi-absorbance-based dose response assay for common IMP-1 and ... | - |
| Beta-lactamase | IC50 | = | 27823.0 | nM | 4.56 | PubChem BioAssay. Epi-absorbance-based dose response assay for common IMP-1 and ... | - |
Data from ChEMBL 36 via Core Engine