Compound Detail
CHEMBL1628270
CYPRODIME BROMIDE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1628270 |
| Name | CYPRODIME BROMIDE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UXENCGOPJHTEEV-NCBCLDNOSA-N |
| Parent Compound | CHEMBL322796 |
| Active Moiety | CHEMBL322796 |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
355.5
MW (Da)
3.11
ALogP
4
HBA
0
HBD
38.8
PSA (Ų)
0.83
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 7.62
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mu-type opioid receptor CHEMBL4354 | Ki | 7.62 | 7.62 | 23.7 | 1 |
| Kappa-type opioid receptor CHEMBL3952 | Ki | 7.21 | 7.21 | 61.1 | 1 |
| Delta-type opioid receptor CHEMBL236 | Ki | 6.98 | 6.98 | 105.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mu-type opioid receptor | Ki | = | 23.7 | nM | 7.62 | Binding affinity by its ability to displace [3H]DAMGO from mu receptor in homoge... | - |
| Kappa-type opioid receptor | Ki | = | 61.1 | nM | 7.21 | Binding affinity by its ability to displace [3H]-U-69,593 from kappa receptor in... | - |
| Delta-type opioid receptor | Ki | = | 105.0 | nM | 6.98 | Binding affinity by its ability to displace [3H]DPDPE from delta receptor in hom... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(95)00325-N | Mu-type opioid receptor | 1 |
| - | 10.1016/0960-894X(95)00325-N | Delta-type opioid receptor | 1 |
| - | 10.1016/0960-894X(95)00325-N | Kappa-type opioid receptor | 1 |
Data from ChEMBL 36 via Core Engine