Compound Detail
CHEMBL1631695
FEXINIDAZOLE SULFOXIDE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1631695 |
| Name | FEXINIDAZOLE SULFOXIDE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HBDLZYHJBXDDJM-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
295.3
MW (Da)
1.64
ALogP
6
HBA
0
HBD
93.2
PSA (Ų)
0.47
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 5.85
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Trypanosoma brucei CHEMBL612849 | EC50 | 5.85 | 5.09 | 1400.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Trypanosoma brucei | EC50 | = | 1400.0 | nM | 5.85 | Antimicrobial activity against Trypanosoma brucei | 20439607 |
| Trypanosoma brucei | EC50 | = | 18400.0 | nM | 4.74 | Antimicrobial activity against Trypanosoma brucei NfxR1 | 20439607 |
| Trypanosoma brucei | EC50 | = | 21000.0 | nM | 4.68 | Antimicrobial activity against Trypanosoma brucei NfxR2 | 20439607 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20439607 | 10.1128/aac.00332-10 | Trypanosoma brucei | 5 |
Data from ChEMBL 36 via Core Engine