Compound Detail
CHEMBL1643077
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1643077 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PEGPSDJOQMWZAB-OALUTQOASA-N |
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
363.4
MW (Da)
1.99
ALogP
3
HBA
4
HBD
94.2
PSA (Ų)
0.56
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas. best 6.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 6.92 | 6.5375 | 120.0 | 4 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | IC50 | = | 120.0 | nM | 6.92 | Antiplatelet activity against pig platelet assessed as inhibition of ADP-induced... | 21193315 |
| NON-PROTEIN TARGET | IC50 | = | 234.0 | nM | 6.63 | Antiplatelet activity against pig platelet assessed as inhibition of thrombin-in... | 21193315 |
| NON-PROTEIN TARGET | IC50 | = | 374.0 | nM | 6.43 | Antiplatelet activity against pig platelet assessed as inhibition of arachidonic... | 21193315 |
| NON-PROTEIN TARGET | IC50 | = | 668.0 | nM | 6.17 | Antiplatelet activity against pig platelet assessed as inhibition of PAF-induced... | 21193315 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21193315 | 10.1016/j.bmc.2010.12.005 | NON-PROTEIN TARGET | 4 |
| 21193315 | 10.1016/j.bmc.2010.12.005 | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine