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Compound Detail

CHEMBL1652472

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CC(C)CCCCCCCCCCCCCCOCCCOP(=O)(O)CO[C@H](CO)Cn1cnc2c(N)ncnc21

Basic Information

ChEMBL ID CHEMBL1652472
Phase Preclinical
Structure Type MOL
InChI Key AFYBRMBNNNXCLD-SANMLTNESA-N
4
Targets
4
Activities
1
Assay Types
0
PK Parameters
11
Publications
0
Known Names

Molecular Properties

599.8
MW (Da)
6.08
ALogP
10
HBA
3
HBD
154.8
PSA (Ų)
0.09
QED
2
Ro5 Violations
26
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C29H54N5O6P
MW 599.75
Aromatic Rings 2
Heavy Atoms 41
NP-Likeness 0.18

Activity Summary

EC50 4 meas. best 7.4

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
NON-PROTEIN TARGET
CHEMBL3879801
EC50 7.4 7.4 40.0 1
Vaccinia virus
CHEMBL613493
EC50 7.4 7.4 40.0 1
Ectromelia virus Moscow
CHEMBL612728
EC50 7.36 7.36 44.0 1
Hepatitis B virus
CHEMBL613497
EC50 7.23 7.23 59.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine