Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL1744446

DEHYDROEBURICOIC ACID
Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
C=C(CC[C@@H](C(=O)O)[C@H]1CC[C@@]2(C)C3=CC[C@H]4C(C)(C)[C@@H](O)CC[C@]4(C)C3=CC[C@]12C)C(C)C

Basic Information

ChEMBL ID CHEMBL1744446
Name DEHYDROEBURICOIC ACID
Phase Preclinical
Structure Type MOL
InChI Key ONFPYGOMAADWAT-OXUZYLMNSA-N

Known Names

Dehydroeburicoicacid
5
Targets
5
Activities
1
Assay Types
0
PK Parameters
13
Publications
1
Known Names

Molecular Properties

468.7
MW (Da)
7.57
ALogP
2
HBA
2
HBD
57.5
PSA (Ų)
0.40
QED
1
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C31H48O3
MW 468.72
Aromatic Rings 0
Heavy Atoms 34
NP-Likeness 3.45

Activity Summary

IC50 5 meas. best 5.22

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
HL-60
CHEMBL383
IC50 5.22 5.22 6000.0 1
CCRF-CEM
CHEMBL382
IC50 5.2 5.2 6300.0 1
MOLT-4
CHEMBL614177
IC50 4.84 4.84 14300.0 1
K562
CHEMBL385
IC50 4.59 4.59 25600.0 1
Neutrophil
CHEMBL613710
IC50 4.11 4.11 77500.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine