Compound Detail
CHEMBL1766569
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Basic Information
| ChEMBL ID | CHEMBL1766569 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BULBNMFBNXNKJA-VQHVLOKHSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
367.4
MW (Da)
3.44
ALogP
5
HBA
1
HBD
59.0
PSA (Ų)
0.63
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.56
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neutrophil CHEMBL613710 | IC50 | 5.56 | 5.36 | 2760.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neutrophil | IC50 | = | 2760.0 | nM | 5.56 | Inhibition of FMLP/CB-stimulated superoxide anion generation in human neutrophil... | 21441032 |
| Neutrophil | IC50 | = | 6970.0 | nM | 5.16 | Inhibition of FMLP/CB-stimulated elastase release in human neutrophils treated f... | 21441032 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21441032 | 10.1016/j.bmc.2011.02.038 | Neutrophil | 2 |
| 22055718 | 10.1016/j.bmc.2011.08.004 | NON-PROTEIN TARGET | 2 |
Data from ChEMBL 36 via Core Engine