Compound Detail
CHEMBL1789987
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Basic Information
| ChEMBL ID | CHEMBL1789987 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VGRINWVKDAYADW-UHFFFAOYSA-L |
| Parent Compound | CHEMBL1198978 |
| Active Moiety | CHEMBL1198978 |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
200.3
MW (Da)
1.35
ALogP
0
HBA
0
HBD
7.8
PSA (Ų)
0.66
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Polyadenylate-binding protein 1 CHEMBL1293286 | IC50 | 5.43 | 5.43 | 3685.0 | 1 |
| Eukaryotic translation initiation factor 4H CHEMBL1293274 | IC50 | 4.01 | 4.01 | 96500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Polyadenylate-binding protein 1 | IC50 | = | 3685.0 | nM | 5.43 | PUBCHEM_BIOASSAY: uHTS fluorescence polarization assay for the identification of... | - |
| Eukaryotic translation initiation factor 4H | IC50 | = | 96500.0 | nM | 4.01 | PUBCHEM_BIOASSAY: uHTS fluorescence polarization assay for the identification of... | - |
Data from ChEMBL 36 via Core Engine