Compound Detail
CHEMBL1790478
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Basic Information
| ChEMBL ID | CHEMBL1790478 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SXTVBRRFCBSWSJ-VQVTYTSYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
216.1
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 6.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dipeptidyl peptidase 4 CHEMBL284 | IC50 | 6.72 | 6.72 | 190.0 | 1 |
| Dipeptidyl peptidase 2 CHEMBL3976 | IC50 | 6.14 | 6.14 | 730.0 | 1 |
| Prolyl endopeptidase CHEMBL3202 | IC50 | 5.22 | 5.22 | 6000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dipeptidyl peptidase 4 | IC50 | = | 190.0 | nM | 6.72 | In vitro for inhibition of Dipeptidylpeptidase IV. | 8642568 |
| Dipeptidyl peptidase 2 | IC50 | = | 730.0 | nM | 6.14 | Compound was tested in vitro for inhibition of Dipeptidylpeptidase II | 8642568 |
| Prolyl endopeptidase | IC50 | = | 6000.0 | nM | 5.22 | Compound was tested in vitro for inhibition of Prolyl endopeptidase | 8642568 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8642568 | 10.1021/jm950732f | Dipeptidyl peptidase 4 | 1 |
| 8642568 | 10.1021/jm950732f | Dipeptidyl peptidase 2 | 1 |
| 8642568 | 10.1021/jm950732f | Prolyl endopeptidase | 1 |
Data from ChEMBL 36 via Core Engine