Compound Detail
CHEMBL1907720
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1907720 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NCGZTSQZDOOYTO-XMMPIXPASA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
436.5
MW (Da)
5.02
ALogP
3
HBA
1
HBD
72.2
PSA (Ų)
0.48
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 6.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cholecystokinin receptor CHEMBL2096986 | IC50 | 6.16 | 6.16 | 700.0 | 1 |
| Gastrin/cholecystokinin type B receptor CHEMBL298 | IC50 | 4.89 | 4.89 | 13000.0 | 1 |
| Cholecystokinin receptor type A CHEMBL3501 | IC50 | 4.52 | 4.52 | 30000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cholecystokinin receptor | IC50 | = | 700.0 | nM | 6.16 | Half-maximal inhibition of [125I]-CCK-33 binding to rat pancreas cholecystokinin... | 2885419 |
| Gastrin/cholecystokinin type B receptor | IC50 | = | 13000.0 | nM | 4.89 | Half-maximal inhibition of binding of [125I]gastrin to guinea pig gastric glands | 2885419 |
| Cholecystokinin receptor type A | IC50 | = | 30000.0 | nM | 4.52 | Half-maximal inhibition of [125I]CCK-33 binding to guinea pig brain(cortex) chol... | 2885419 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2885419 | 10.1021/jm00390a019 | Cholecystokinin receptor | 1 |
| 2885419 | 10.1021/jm00390a019 | Cholecystokinin receptor type A | 1 |
| 2885419 | 10.1021/jm00390a019 | Gastrin/cholecystokinin type B receptor | 1 |
Data from ChEMBL 36 via Core Engine