Compound Detail
CHEMBL1966143
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Basic Information
| ChEMBL ID | CHEMBL1966143 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CIYPTMSDKNRLGL-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
426.4
MW (Da)
4.01
ALogP
6
HBA
2
HBD
107.5
PSA (Ų)
0.48
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 5.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Megakaryocyte-associated tyrosine-protein kinase CHEMBL4175 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Serine/threonine-protein kinase BRSK1 CHEMBL5650 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Interleukin-1 receptor-associated kinase 1 CHEMBL3357 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Megakaryocyte-associated tyrosine-protein kinase | Ki | = | 1584.89 | nM | 5.8 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| Serine/threonine-protein kinase BRSK1 | Ki | = | 5011.87 | nM | 5.3 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| Interleukin-1 receptor-associated kinase 1 | Ki | = | 6309.57 | nM | 5.2 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
Data from ChEMBL 36 via Core Engine