Compound Detail
CHEMBL1991853
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1991853 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QVMKLKBODZHJDK-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
286.8
MW (Da)
3.40
ALogP
5
HBA
0
HBD
62.5
PSA (Ų)
0.68
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.54
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 10 CHEMBL2637 | IC50 | 6.54 | 6.54 | 290.0 | 1 |
| Mitogen-activated protein kinase 9 CHEMBL4179 | IC50 | 6.3 | 6.3 | 500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 10 | IC50 | = | 290.0 | nM | 6.54 | Inhibition of recombinant pre-activated GST-tagged JNK3 (unknown origin) using b... | - |
| Mitogen-activated protein kinase 9 | IC50 | = | 500.0 | nM | 6.3 | Inhibition of recombinant pre-activated GST-tagged JNK2 (unknown origin) using b... | - |
Data from ChEMBL 36 via Core Engine