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Compound Detail

CHEMBL1999960

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O=[N+]([O-])c1ccc(/C=N/n2cnc3ccccc32)s1

Basic Information

ChEMBL ID CHEMBL1999960
Phase Preclinical
Structure Type MOL
InChI Key REXSYOASIGFOSW-VGOFMYFVSA-N
1
Targets
4
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

272.3
MW (Da)
2.89
ALogP
6
HBA
0
HBD
73.3
PSA (Ų)
0.42
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C12H8N4O2S
MW 272.29
Aromatic Rings 3
Heavy Atoms 19
NP-Likeness -2.24

Activity Summary

EC50 2 meas. best 6.59
IC50 2 meas. best 4.33

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 6.59 5.925 257.0 2
Unchecked
CHEMBL612545
IC50 4.33 4.185 46828.0 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine