Compound Detail
CHEMBL2000934
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Basic Information
| ChEMBL ID | CHEMBL2000934 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZIVDOOQUJQJBDA-UHFFFAOYSA-N |
4
Targets
4
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
360.3
MW (Da)
4.86
ALogP
3
HBA
2
HBD
66.9
PSA (Ų)
0.70
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 4 meas. best 7.2
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cyclin-dependent kinase 8 CHEMBL5719 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Mast/stem cell growth factor receptor Kit CHEMBL1936 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Activin receptor type-1 CHEMBL5903 | Ki | 6.1 | 6.1 | 794.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cyclin-dependent kinase 8 | Ki | = | 63.1 | nM | 7.2 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| Mast/stem cell growth factor receptor Kit | Ki | = | 199.53 | nM | 6.7 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| Dual specificity protein kinase CLK4 | Ki | = | 251.19 | nM | 6.6 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
| Activin receptor type-1 | Ki | = | 794.33 | nM | 6.1 | PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member na... | - |
Data from ChEMBL 36 via Core Engine