Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL2105510

ZINTEROL HYDROCHLORIDE
Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CC(C)(Cc1ccccc1)NCC(O)c1ccc(O)c(NS(C)(=O)=O)c1.Cl
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL2105510
Name ZINTEROL HYDROCHLORIDE
Phase Preclinical
Structure Type MOL
InChI Key LVNUBJDWJFOMKH-UHFFFAOYSA-N
Parent Compound CHEMBL1243407
Active Moiety CHEMBL1243407

Known Names

MJ 9184-1 MJ-9184-1 NSC-284704 Zinterol hcl Zinterol hydrochloride
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
20
Publications
5
Known Names

Molecular Properties

378.5
MW (Da)
2.41
ALogP
5
HBA
4
HBD
98.7
PSA (Ų)
0.53
QED
0
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Racemic
USAN Stem -terol
USAN Year 1977

Extended Properties

Molecular Formula C19H27ClN2O4S
MW 414.96
Aromatic Rings 2
Heavy Atoms 26
NP-Likeness -0.51

Activity Summary

EC50 1 meas. best 7.45

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Beta-2 adrenergic receptor
CHEMBL210
 EC50 7.45 7.45 35.7 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Beta-2 adrenergic receptor EC50 = 35.66 nM 7.45 GPCR PRESTO-Tango dose-response in agonist mode with target: ADRB2 -

Literature References

PubMed DOI Target Context # Activities
- 10.6019/CHEMBL4689842 HEK-293T 10
- 10.6019/CHEMBL5209801 Apelin receptor 8
- 10.6019/CHEMBL5209801 Glucagon-like peptide 1 receptor 8
- 10.6019/CHEMBL5209801 Type-1 angiotensin II receptor 8
- 10.6019/CHEMBL5209801 Glucose-dependent insulinotropic receptor 8
- 10.6019/CHEMBL5209801 Adhesion G-protein coupled receptor F1 8
- 10.6019/CHEMBL5209801 C5a anaphylatoxin chemotactic receptor 1 8
- 10.6019/CHEMBL5209801 Alpha-2A adrenergic receptor 8
- 10.6019/CHEMBL5209801 N-formyl peptide receptor 2 8
- 10.6019/CHEMBL5209801 CX3C chemokine receptor 1 8
- 10.6019/CHEMBL4689842 U2OS 8
- 10.6019/CHEMBL5209801 Free fatty acid receptor 4 8
- 10.6019/CHEMBL5209801 Beta-2 adrenergic receptor 8
- 10.6019/CHEMBL5209801 Sphingosine 1-phosphate receptor 1 8
5607 10.1021/jm00227a010 Rattus norvegicus 3
- 10.6019/CHEMBL4689842 Fibroblast 3
- 10.6019/CHEMBL5209801 G-protein coupled receptor 35 2
- 10.6019/CHEMBL5442687 Beta-2 adrenergic receptor 2
5607 10.1021/jm00227a010 ADMET 2
- 10.6019/CHEMBL5060014 Bromodomain-containing protein 4 1

Data from ChEMBL 36 via Core Engine