Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL2111058

SUNEPITRON
🧪 Phase II
Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
🧪 Phase II
O=C1CCC(=O)N1C[C@H]1CC[C@H]2CN(c3ncccn3)CCN2C1

Basic Information

ChEMBL ID CHEMBL2111058
Name SUNEPITRON
Phase Phase II
Structure Type MOL
InChI Key UXWBIYCPUVWKHP-KBPBESRZSA-N

Known Names

CP 93393 CP-93,393 CP-93393 Sunepitron
2
Targets
2
Activities
1
Assay Types
1
PK Parameters
4
Publications
4
Known Names

Molecular Properties

329.4
MW (Da)
0.53
ALogP
6
HBA
0
HBD
69.6
PSA (Ų)
0.75
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Single Enantiomer
USAN Year 1997

Extended Properties

Molecular Formula C17H23N5O2
MW 329.40
Aromatic Rings 1
Heavy Atoms 24
NP-Likeness -1.43

Activity Summary

Ki 2 meas. best 7.46

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Adrenergic receptor alpha-1
CHEMBL1907610
Ki 7.46 7.46 35.0 1
5-hydroxytryptamine receptor 1A
CHEMBL214
Ki 7.04 7.04 92.0 1

Pharmacokinetic Data

Parameter Value Units Species
T1/2 2.0 hr Homo sapiens

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
16722631 10.1021/jm0508641 5-hydroxytryptamine receptor 1A 1
16722631 10.1021/jm0508641 Adrenergic receptor alpha-1 1
16722631 10.1021/jm0508641 Unchecked 1
16722631 10.1021/jm0508641 Homo sapiens 1

Data from ChEMBL 36 via Core Engine