Compound Detail
CHEMBL23393
SODIUM LAURYL SULFATE 🧪 Phase III
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🧪 Phase III
Basic Information
| ChEMBL ID | CHEMBL23393 |
| Name | SODIUM LAURYL SULFATE |
| Phase | Phase III |
| Structure Type | MOL |
| InChI Key | DBMJMQXJHONAFJ-UHFFFAOYSA-M |
3
Targets
5
Activities
2
Assay Types
0
PK Parameters
20
Publications
7
Known Names
7
Indications
Molecular Properties
288.4
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Indications
Hypersensitivity Infections Lice Infestations Pain Skin Diseases Tendinopathy Tinea Pedis
Activity Summary
IC50 4 meas. best 9.65
Ki 1 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| ADMET CHEMBL612558 | IC50 | 9.65 | 9.65 | 0.2 | 1 |
| Unchecked CHEMBL612545 | Ki | 5.7 | 5.7 | 2000.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 5.64 | 5.64 | 2300.0 | 1 |
| Bifunctional epoxide hydrolase 2 CHEMBL2409 | IC50 | 5.26 | 5.26 | 5500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| ADMET | IC50 | = | 0.222 | nM | 9.65 | Cytotoxicity against human HepG2/C3A cells after 24 hrs by neutral red uptake as... | 22182928 |
| Unchecked | Ki | = | 2000.0 | nM | 5.7 | Displacement of C18-Aib-lucifer yellow from HIV1 envelope glycoprotein gp41 Fe(e... | 19534533 |
| Unchecked | IC50 | = | 2300.0 | nM | 5.64 | Inhibition of hexa-His-tagged human soluble epoxide hydrolase N-terminal phospha... | 31436984 |
| Bifunctional epoxide hydrolase 2 | IC50 | = | 5500.0 | nM | 5.26 | Inhibition of phosphatase activity of full length human soluble epoxide hydrolas... | 31436984 |
Literature References
Data from ChEMBL 36 via Core Engine