Compound Detail
CHEMBL267809
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL267809 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OXCBPWVHMRRTNH-UHFFFAOYSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
479.6
MW (Da)
4.83
ALogP
7
HBA
1
HBD
94.3
PSA (Ų)
0.33
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.35
Kd 1 meas. best 8.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Angiotensin II receptor CHEMBL2094256 | Kd | 8.7 | 8.7 | 2.0 | 1 |
| Angiotensin II receptor CHEMBL2094112 | IC50 | 8.35 | 8.35 | 4.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Angiotensin II receptor | Kd | = | 1.995 | nM | 8.7 | Compound was tested for antagonism of Angiotensin II-contracted rabbit aortic ri... | - |
| Angiotensin II receptor | IC50 | = | 4.5 | nM | 8.35 | Inhibition of [125I]-AII binding to Angiotensin II receptor of rat uterine membr... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(00)80286-3 | Angiotensin II receptor | 2 |
Data from ChEMBL 36 via Core Engine