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Compound Detail

CHEMBL290723

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C[C@@H]1O[C@@H](C[N+](C)(C)C)CC1=O

Basic Information

ChEMBL ID CHEMBL290723
Phase Preclinical
Structure Type MOL
InChI Key XKOQIVSZENKHPJ-JGVFFNPUSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

172.2
MW (Da)
0.44
ALogP
2
HBA
0
HBD
26.3
PSA (Ų)
0.56
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C9H18NO2+
MW 172.25
Aromatic Rings 0
Heavy Atoms 12
NP-Likeness 1.15

Activity Summary

Ki 2 meas. best 9.12

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
Ki 9.12 9.12 0.8 1
Muscarinic acetylcholine receptor
CHEMBL1907609
Ki 6.16 6.16 700.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
7739014 10.1021/jm00009a016 Muscarinic acetylcholine receptor 3
7739014 10.1021/jm00009a016 Unchecked 1

Data from ChEMBL 36 via Core Engine