Compound Detail
CHEMBL308524
IOXIPRIDE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL308524 |
| Name | IOXIPRIDE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BKJGKGPGPACEQW-JTQLQIEISA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
434.3
MW (Da)
2.23
ALogP
5
HBA
2
HBD
71.0
PSA (Ų)
0.67
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 10.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(2) dopamine receptor CHEMBL339 | Ki | 10.72 | 10.72 | 0.0 | 1 |
| D(3) dopamine receptor CHEMBL234 | Ki | 9.8 | 9.8 | 0.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(2) dopamine receptor | Ki | = | 0.019 | nM | 10.72 | Inhibition constant against dopamine receptor D2 in rat | 8093734 |
| D(3) dopamine receptor | Ki | = | 0.16 | nM | 9.8 | In vitro binding affinity on D3 receptor is inhibition of binding of [125I]- NCQ... | 8246241 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8246241 | 10.1021/jm00075a028 | D(3) dopamine receptor | 1 |
| 8093734 | 10.1021/jm00054a005 | D(2) dopamine receptor | 1 |
Data from ChEMBL 36 via Core Engine