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Compound Detail

CHEMBL3189237

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Cn1/c(=N\C(=O)CCl)sc2ccccc21

Basic Information

ChEMBL ID CHEMBL3189237
Phase Preclinical
Structure Type MOL
InChI Key OSJWKPHEUAQQKR-ZRDIBKRKSA-N
1
Targets
4
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

240.7
MW (Da)
1.91
ALogP
3
HBA
0
HBD
34.4
PSA (Ų)
0.70
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C10H9ClN2OS
MW 240.72
Aromatic Rings 2
Heavy Atoms 15
NP-Likeness -2.34

Activity Summary

IC50 3 meas. best 6.23
EC50 1 meas. best 6.01

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 6.23 5.61 590.0 3
Unchecked
CHEMBL612545
EC50 6.01 6.01 973.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine