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Compound Detail

CHEMBL3194093

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O=C(Nc1ccccc1C(=O)N/N=C/c1ccc(O)cc1)c1ccccc1

Basic Information

ChEMBL ID CHEMBL3194093
Phase Preclinical
Structure Type MOL
InChI Key KNYSRDQTRDCONU-HYARGMPZSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

359.4
MW (Da)
3.41
ALogP
4
HBA
3
HBD
90.8
PSA (Ų)
0.48
QED
0
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C21H17N3O3
MW 359.39
Aromatic Rings 3
Heavy Atoms 27
NP-Likeness -1.32

Activity Summary

EC50 2 meas. best 6.74

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Luciferin 4-monooxygenase
CHEMBL5567
EC50 6.74 6.74 184.0 1
Unchecked
CHEMBL612545
EC50 5.44 5.44 3654.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine