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Compound Detail

CHEMBL3198581

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O=C(N/N=C\c1ccc([N+](=O)[O-])s1)c1cncc(Br)c1

Basic Information

ChEMBL ID CHEMBL3198581
Phase Preclinical
Structure Type MOL
InChI Key YEDSXCJEAFAHKT-NSIKDUERSA-N
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

355.2
MW (Da)
2.58
ALogP
6
HBA
1
HBD
97.5
PSA (Ų)
0.52
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C11H7BrN4O3S
MW 355.17
Aromatic Rings 2
Heavy Atoms 20
NP-Likeness -2.80

Activity Summary

EC50 4 meas. best 6.34

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 6.34 5.5525 452.0 4

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine