Compound Detail
CHEMBL350283
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Basic Information
| ChEMBL ID | CHEMBL350283 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ITEDDYPYHIHWHC-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
261.8
MW (Da)
3.82
ALogP
2
HBA
2
HBD
46.2
PSA (Ų)
0.81
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.99
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Progesterone receptor CHEMBL208 | IC50 | 6.99 | 6.755 | 103.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Progesterone receptor | IC50 | = | 103.0 | nM | 6.99 | Antagonistic activity against Progesterone receptor (PR) in transcriptional acti... | 11859003 |
| Progesterone receptor | IC50 | = | 301.0 | nM | 6.52 | Binding affinity against progesterone receptor using human T47D breast carcinoma... | 11859003 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11859003 | 10.1016/s0960-894x(02)00025-2 | Progesterone receptor | 3 |
Data from ChEMBL 36 via Core Engine