Compound Detail
CHEMBL355063
BENDAZOL 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL355063 |
| Name | BENDAZOL |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | YTLQFZVCLXFFRK-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
2
Known Names
Molecular Properties
208.3
MW (Da)
3.15
ALogP
1
HBA
1
HBD
28.7
PSA (Ų)
0.69
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Activity Summary
IC50 2 meas. best 4.74
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.74 | 4.74 | 18400.0 | 1 |
| Cytochrome P450 2B1 CHEMBL3335 | IC50 | 4.04 | 4.04 | 91201.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 18400.0 | nM | 4.74 | Inhibition of LPS induced NF-kappa-B transcriptional activity in mouse RAW264.7 ... | 26976506 |
| Cytochrome P450 2B1 | IC50 | = | 91201.08 | nM | 4.04 | Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic micro... | 7120277 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 26976506 | 10.1016/j.bmc.2016.03.012 | Unchecked | 2 |
| 7120277 | 10.1021/jm00350a002 | Cytochrome P450 2B1 | 1 |
| 7120277 | 10.1021/jm00350a002 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine