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Compound Detail

CHEMBL3582005

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CCC(C)C(=O)O[C@@]12[C@H](OC(C)=O)[C@@H](C)[C@@]3(O)[C@@H](C=C(CO)C[C@]4(O)C(=O)C(C)=C[C@@H]34)[C@@H]1C2(C)C

Basic Information

ChEMBL ID CHEMBL3582005
Phase Preclinical
Structure Type MOL
InChI Key LJNNQVFOVQWDMN-CBVZBMKRSA-N
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
11
Publications
0
Known Names

Molecular Properties

490.6
MW (Da)
2.10
ALogP
8
HBA
3
HBD
130.4
PSA (Ų)
0.39
QED
0
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C27H38O8
MW 490.59
Aromatic Rings 0
Heavy Atoms 35
NP-Likeness 3.09

Activity Summary

EC50 3 meas. best 6.97

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Human immunodeficiency virus 2
CHEMBL380
EC50 6.97 6.97 107.0 1
Human immunodeficiency virus 1
CHEMBL378
EC50 6.57 6.57 271.0 1
NON-PROTEIN TARGET
CHEMBL3879801
EC50 5.48 5.48 3300.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine