Compound Detail
CHEMBL3785213
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3785213 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DPJVLCNBELPWBX-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
351.4
MW (Da)
2.81
ALogP
7
HBA
1
HBD
92.5
PSA (Ų)
0.56
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.01
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatocyte growth factor receptor CHEMBL3717 | IC50 | 8.01 | 8.01 | 9.8 | 1 |
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 6.8 | 6.8 | 160.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatocyte growth factor receptor | IC50 | = | 9.8 | nM | 8.01 | Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as sub... | 27017548 |
| NON-PROTEIN TARGET | IC50 | = | 160.0 | nM | 6.8 | Cytotoxicity against human EBC1 cells assessed as inhibition of cell proliferati... | 27017548 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 27017548 | 10.1016/j.ejmech.2016.03.027 | NON-PROTEIN TARGET | 1 |
| 27017548 | 10.1016/j.ejmech.2016.03.027 | Hepatocyte growth factor receptor | 1 |
Data from ChEMBL 36 via Core Engine