Compound Detail
CHEMBL4244830
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4244830 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SWZBGLPNJVKLSU-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
270.4
MW (Da)
3.04
ALogP
3
HBA
2
HBD
37.2
PSA (Ų)
0.88
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | IC50 | 5.46 | 5.19 | 3500.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | IC50 | = | 3500.0 | nM | 5.46 | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum D10 ... | 29571157 |
| Plasmodium falciparum | IC50 | = | 8600.0 | nM | 5.07 | Gametocytocidal activity against Plasmodium falciparum 3D7 elo1-pfs16-CBG99 late... | 29571157 |
| Plasmodium falciparum | IC50 | = | 9100.0 | nM | 5.04 | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 a... | 29571157 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29571157 | 10.1016/j.ejmech.2018.03.024 | Plasmodium falciparum | 5 |
Data from ChEMBL 36 via Core Engine