Compound Detail
CHEMBL432337
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL432337 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SNJAJGBRRRRMGT-RVDMUPIBSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
329.5
MW (Da)
4.62
ALogP
2
HBA
1
HBD
40.5
PSA (Ų)
0.80
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rattus norvegicus CHEMBL376 | IC50 | 7.52 | 7.52 | 30.0 | 1 |
| Homo sapiens CHEMBL372 | IC50 | 6.82 | 6.82 | 150.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rattus norvegicus | IC50 | = | 30.0 | nM | 7.52 | Compound is evaluated for inhibitory effect on the generation of Prostaglandin E... | 3118023 |
| Homo sapiens | IC50 | = | 150.0 | nM | 6.82 | Compound is evaluated for inhibitory effect on the generation of Leukotriene B4 ... | 3118023 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3118023 | 10.1021/jm00394a011 | Rattus norvegicus | 8 |
| 3118023 | 10.1021/jm00394a011 | Homo sapiens | 1 |
Data from ChEMBL 36 via Core Engine