Compound Detail
CHEMBL4459178
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Basic Information
| ChEMBL ID | CHEMBL4459178 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XOFSNWGPOPTYBO-ZROIWOOFSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
368.4
MW (Da)
3.61
ALogP
5
HBA
2
HBD
91.2
PSA (Ų)
0.54
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.08
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Myc proto-oncogene protein CHEMBL1250348 | IC50 | 6.08 | 6.08 | 830.0 | 1 |
| Lymphoma cell line CHEMBL614114 | IC50 | 4.93 | 4.93 | 11790.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Myc proto-oncogene protein | IC50 | = | 830.0 | nM | 6.08 | Inhibition of Myc (unknown origin) expressed in HEK293T cells incubated for 16 h... | - |
| Lymphoma cell line | IC50 | = | 11790.0 | nM | 4.93 | Cytotoxicity against mouse E-mu-Myc lymphoma cells assessed as decrease in cell ... | - |
Data from ChEMBL 36 via Core Engine