Compound Detail
CHEMBL4565580
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Basic Information
| ChEMBL ID | CHEMBL4565580 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GTDNROOVOBKLDL-UHFFFAOYSA-N |
3
Targets
7
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
322.3
MW (Da)
3.26
ALogP
5
HBA
2
HBD
79.4
PSA (Ų)
0.77
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 6 meas. best 8.7
EC50 1 meas. best 5.41
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase LATS1 CHEMBL6167 | IC50 | 8.7 | 8.7 | 2.0 | 2 |
| Serine/threonine-protein kinase LATS2 CHEMBL5907 | IC50 | 7.82 | 7.82 | 15.0 | 2 |
| Serine/threonine-protein kinase LATS CHEMBL4523992 | IC50 | 5.52 | 5.285 | 2990.0 | 2 |
| Serine/threonine-protein kinase LATS CHEMBL4523992 | EC50 | 5.41 | 5.41 | 3880.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine