Compound Detail
CHEMBL498296
FUTOQUINOL Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL498296 |
| Name | FUTOQUINOL |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AOZTYYBGNNXAOI-NTEUORMPSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
354.4
MW (Da)
3.82
ALogP
5
HBA
0
HBD
54.0
PSA (Ų)
0.73
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.88
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 4.88 | 4.88 | 13100.0 | 1 |
| BV-2 CHEMBL614781 | IC50 | 4.78 | 4.78 | 16800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | IC50 | = | 13100.0 | nM | 4.88 | Antiinflammatory activity in human PMN assessed as inhibition of Phorbol-12-myri... | 16724856 |
| BV-2 | IC50 | = | 16800.0 | nM | 4.78 | Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-... | 19900811 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19900811 | 10.1016/j.bmcl.2009.10.016 | BV-2 | 3 |
| 16724856 | 10.1021/np0505521 | NON-PROTEIN TARGET | 1 |
Data from ChEMBL 36 via Core Engine