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Compound Detail

CHEMBL518887

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CCC(C)C(=O)O[C@@]12C[C@@H](C)[C@@]3(O)[C@@H](C=C(CO)C[C@]4(O)C(=O)C(C)=C[C@@H]34)[C@@H]1C2(C)C

Basic Information

ChEMBL ID CHEMBL518887
Phase Preclinical
Structure Type MOL
InChI Key UTWPUNYNNNYPEZ-ABNKIXKLSA-N
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
12
Publications
0
Known Names

Molecular Properties

432.6
MW (Da)
2.56
ALogP
6
HBA
3
HBD
104.1
PSA (Ų)
0.47
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C25H36O6
MW 432.56
Aromatic Rings 0
Heavy Atoms 31
NP-Likeness 3.04

Activity Summary

EC50 3 meas. best 7.25

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Human immunodeficiency virus 2
CHEMBL380
EC50 7.25 7.25 56.0 1
Human immunodeficiency virus 1
CHEMBL378
EC50 6.89 6.89 129.0 1
NON-PROTEIN TARGET
CHEMBL3879801
EC50 5.92 5.92 1200.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine