Compound Detail
CHEMBL5199343
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5199343 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BYDOTJMKOMWDQU-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
291.2
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Replicase polyprotein 1ab CHEMBL4523582 | IC50 | 7.3 | 6.77 | 49.5 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Replicase polyprotein 1ab | IC50 | = | 49.55 | nM | 7.3 | Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) ... | 35620927 |
| Replicase polyprotein 1ab | IC50 | = | 578.0 | nM | 6.24 | Inhibition of SARS-CoV-2 papain-like protease expressed in Escherichia coli BL21... | 35620927 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35620927 | 10.1021/acs.jmedchem.2c00303 | Replicase polyprotein 1ab | 2 |
Data from ChEMBL 36 via Core Engine