Compound Detail
CHEMBL549701
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Basic Information
| ChEMBL ID | CHEMBL549701 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UYBVBIGUZFLJFY-RMPHRYRLSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
308.3
MW (Da)
-0.75
ALogP
8
HBA
4
HBD
129.1
PSA (Ų)
0.58
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 4.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen phosphorylase, muscle form CHEMBL4696 | Ki | 4.57 | 4.38 | 27000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glycogen phosphorylase, muscle form | Ki | = | 27000.0 | nM | 4.57 | Inhibition of rabbit muscle glycogen phosphorylase b | 24608000 |
| Glycogen phosphorylase, muscle form | Ki | = | 64000.0 | nM | 4.19 | Inhibition of rabbit muscle glycogen phosphorylase b | 19450985 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19450985 | 10.1016/j.bmc.2009.04.036 | Glycogen phosphorylase, muscle form | 1 |
| 24608000 | 10.1016/j.ejmech.2014.02.041 | Glycogen phosphorylase, muscle form | 1 |
Data from ChEMBL 36 via Core Engine