Compound Detail
CHEMBL574554
QUINOSUAVEOLINE B Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL574554 |
| Name | QUINOSUAVEOLINE B |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OXDIHTWLYDWMMZ-CQSZACIVSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
315.3
MW (Da)
2.90
ALogP
6
HBA
1
HBD
74.0
PSA (Ų)
0.78
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.84
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neutrophil CHEMBL613710 | IC50 | 4.84 | 4.84 | 14500.0 | 1 |
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 4.25 | 4.25 | 56800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neutrophil | IC50 | = | 14500.0 | nM | 4.84 | Immunomodulatory activity in polymorphoneutrophils assessed as inhibition of lum... | 18950230 |
| NON-PROTEIN TARGET | IC50 | = | 56800.0 | nM | 4.25 | Immunomodulatory activity in whole blood assessed as inhibition of luminol-induc... | 18950230 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18950230 | 10.1021/np800276f | Neutrophil | 3 |
| 18950230 | 10.1021/np800276f | NON-PROTEIN TARGET | 1 |
Data from ChEMBL 36 via Core Engine