Compound Detail
CHEMBL5824868
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Basic Information
| ChEMBL ID | CHEMBL5824868 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MQHXRECXBSFFAH-VGMNWLOBSA-N |
7
Targets
14
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
228.1
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 14 meas. best 6.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.8 | 6.8 | 160.0 | 1 |
| Dipeptidyl peptidase 4 CHEMBL284 | IC50 | 5.7 | 5.7 | 2000.0 | 1 |
| Dipeptidyl peptidase 9 CHEMBL4793 | IC50 | 5.52 | 5.52 | 3000.0 | 1 |
| Dipeptidyl peptidase 8 CHEMBL4657 | IC50 | 5.22 | 5.22 | 6000.0 | 1 |
| Dipeptidyl peptidase 8/9 CHEMBL3885564 | IC50 | 4.92 | 4.92 | 12000.0 | 1 |
| Dipeptidyl peptidase 2 CHEMBL3976 | IC50 | 4.92 | 4.92 | 12000.0 | 1 |
| Prolyl endopeptidase FAP CHEMBL4683 | IC50 | 4.58 | 4.58 | 26000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 160.0 | nM | 6.8 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Dipeptidyl peptidase 4 | IC50 | = | 2000.0 | nM | 5.7 | In Vitro Inhibition Assay: EnzymesRecombinant human DPPIV (R&D Systems, Cat. No.... | - |
| Dipeptidyl peptidase 9 | IC50 | = | 3000.0 | nM | 5.52 | In Vitro Inhibition Assay: EnzymesRecombinant human DPPIV (R&D Systems, Cat. No.... | - |
| Dipeptidyl peptidase 8 | IC50 | = | 6000.0 | nM | 5.22 | In Vitro Inhibition Assay: EnzymesRecombinant human DPPIV (R&D Systems, Cat. No.... | - |
| Dipeptidyl peptidase 2 | IC50 | = | 12000.0 | nM | 4.92 | In Vitro Inhibition Assay: EnzymesRecombinant human DPPIV (R&D Systems, Cat. No.... | - |
| Dipeptidyl peptidase 8/9 | IC50 | = | 12000.0 | nM | 4.92 | In Vitro Inhibition Assay: EnzymesRecombinant human DPPIV (R&D Systems, Cat. No.... | - |
| Prolyl endopeptidase FAP | IC50 | = | 26000.0 | nM | 4.58 | In Vitro Inhibition Assay: EnzymesRecombinant human DPPIV (R&D Systems, Cat. No.... | - |
Data from ChEMBL 36 via Core Engine