Compound Detail
CHEMBL594972
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Basic Information
| ChEMBL ID | CHEMBL594972 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YLTDNVVQKRHCJP-RKQHYHRCSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
295.3
MW (Da)
-1.02
ALogP
7
HBA
4
HBD
111.7
PSA (Ų)
0.56
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 4.71
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen phosphorylase, muscle form CHEMBL4696 | Ki | 4.71 | 4.71 | 19600.0 | 1 |
| Unchecked CHEMBL612545 | Ki | 4.71 | 4.71 | 19600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glycogen phosphorylase, muscle form | Ki | = | 19600.0 | nM | 4.71 | Inhibition of rabbit muscle glycogen phosphorylase b | 19781947 |
| Unchecked | Ki | = | 19600.0 | nM | 4.71 | Inhibition of rabbit muscle Glycogen phosphorylase b using glucose-1-phosphate a... | 31251604 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19781947 | 10.1016/j.bmc.2009.08.060 | Glycogen phosphorylase, muscle form | 1 |
| 31251604 | 10.1021/acs.jmedchem.9b00356 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine