Compound Detail
CHEMBL607438
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Basic Information
| ChEMBL ID | CHEMBL607438 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PQZVZHFVFJNYNL-DGCLKSJQSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
249.3
MW (Da)
1.94
ALogP
4
HBA
1
HBD
41.9
PSA (Ų)
0.87
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.53
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(2) dopamine receptor CHEMBL339 | IC50 | 5.53 | 5.53 | 2923.0 | 1 |
| Nucleic Acid CHEMBL345 | IC50 | 5.05 | 5.05 | 8900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(2) dopamine receptor | IC50 | = | 2923.0 | nM | 5.53 | Potency to displace the specific in vitro binding of [3H]DP-5,6-ADTN to rat stri... | 2903247 |
| Nucleic Acid | IC50 | = | 8900.0 | nM | 5.05 | Potency to displace the specific in vitro binding of [3H]N-0437 to calf striatal... | 2903247 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2903247 | 10.1021/jm00119a020 | Rattus norvegicus | 3 |
| 2903247 | 10.1021/jm00119a020 | No relevant target | 3 |
| 2903247 | 10.1021/jm00119a020 | D(2) dopamine receptor | 1 |
| 2903247 | 10.1021/jm00119a020 | Nucleic Acid | 1 |
Data from ChEMBL 36 via Core Engine