Compound Detail
CHEMBL69239
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Basic Information
| ChEMBL ID | CHEMBL69239 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RCNIJPUWEALHAZ-KGLIPLIRSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
280.4
MW (Da)
2.02
ALogP
3
HBA
3
HBD
55.1
PSA (Ų)
0.67
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 5.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Aminopeptidase B CHEMBL2452 | Ki | 5.4 | 5.4 | 4000.0 | 1 |
| Aminopeptidase N CHEMBL2590 | Ki | 5.31 | 5.31 | 4900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Aminopeptidase B | Ki | = | 4000.0 | nM | 5.4 | Inhibitory activity against aminopeptidase B | 3184126 |
| Aminopeptidase N | Ki | = | 4900.0 | nM | 5.31 | Inhibitory activity against Aminopeptidase M | 3184126 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3184126 | 10.1021/jm00119a022 | Aminopeptidase N | 1 |
| 3184126 | 10.1021/jm00119a022 | Cytosol aminopeptidase | 1 |
| 3184126 | 10.1021/jm00119a022 | Aminopeptidase B | 1 |
Data from ChEMBL 36 via Core Engine