Compound Detail
CHEMBL73675
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL73675 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QXPWDQWINFEIAQ-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
335.4
MW (Da)
3.42
ALogP
3
HBA
1
HBD
40.5
PSA (Ų)
0.93
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 7.13
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(2) dopamine receptor CHEMBL339 | Ki | 7.13 | 7.13 | 74.1 | 1 |
| D(1A) dopamine receptor CHEMBL265 | Ki | 6.13 | 6.13 | 741.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(2) dopamine receptor | Ki | = | 74.13 | nM | 7.13 | Compound was evaluated for its affinity (pKi) to inhibit [3H]spiperone binding t... | 1676759 |
| D(1A) dopamine receptor | Ki | = | 741.31 | nM | 6.13 | Compound was evaluated for its affinity (pKi) to inhibit [3H]SCH-23390 binding t... | 1676759 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1676759 | 10.1021/jm00111a046 | D(2) dopamine receptor | 1 |
| 1676759 | 10.1021/jm00111a046 | D(1A) dopamine receptor | 1 |
| 1676759 | 10.1021/jm00111a046 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine