Compound Detail
CHEMBL93906
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Basic Information
| ChEMBL ID | CHEMBL93906 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RZKXRZWOXZPSBJ-UHFFFAOYSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
361.4
MW (Da)
4.95
ALogP
5
HBA
1
HBD
61.0
PSA (Ų)
0.32
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.0
Ki 1 meas. best 7.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Progesterone receptor CHEMBL208 | IC50 | 8.0 | 8.0 | 10.0 | 1 |
| Progesterone receptor CHEMBL208 | Ki | 7.52 | 7.52 | 30.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Progesterone receptor | IC50 | = | 10.0 | nM | 8.0 | Inhibitory concentration against progesterone stimulated alkaline phosphatase ac... | 11591515 |
| Progesterone receptor | Ki | = | 30.0 | nM | 7.52 | Binding affinity towards progesterone receptor was measured | 11591515 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11591515 | 10.1016/s0960-894x(01)00554-6 | Progesterone receptor | 3 |
Data from ChEMBL 36 via Core Engine