Compound Detail
CHEMBL97483
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL97483 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JUPUJRCJICHRIW-LURJTMIESA-N |
2
Targets
4
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
158.3
MW (Da)
0.76
ALogP
2
HBA
1
HBD
29.3
PSA (Ų)
0.57
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 4 meas. best 5.84
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dipeptidyl peptidase 2 CHEMBL3976 | Ki | 5.84 | 5.84 | 1430.0 | 2 |
| Dipeptidyl peptidase 4 CHEMBL284 | Ki | 4.32 | 4.32 | 47600.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dipeptidyl peptidase 2 | Ki | = | 1430.0 | nM | 5.84 | Inhibition of Dipeptidyl Peptidase II (Quiescent cell proline peptidase) | 12270155 |
| Dipeptidyl peptidase 2 | Ki | = | 1430.0 | nM | 5.84 | Inhibitory activity of compound against Dipeptidylpeptidase II (DPP II) | 14584950 |
| Dipeptidyl peptidase 4 | Ki | = | 47600.0 | nM | 4.32 | Inhibition of Dipeptidyl Peptidase IV | 12270155 |
| Dipeptidyl peptidase 4 | Ki | = | 47600.0 | nM | 4.32 | Inhibitory activity of compound against Dipeptidylpeptidase IV (DPP IV) | 14584950 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14584950 | 10.1021/jm0308803 | Dipeptidyl peptidase 4 | 2 |
| 12270155 | 10.1016/s0960-894x(02)00603-0 | Dipeptidyl peptidase 2 | 1 |
| 12270155 | 10.1016/s0960-894x(02)00603-0 | Dipeptidyl peptidase 4 | 1 |
| 12270155 | 10.1016/s0960-894x(02)00603-0 | Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4) | 1 |
| 14584950 | 10.1021/jm0308803 | Dipeptidyl peptidase 2 | 1 |
Data from ChEMBL 36 via Core Engine