Glucocorticoid receptor · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P06536. Use UniProt P06536 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P06536 as the stable identity anchor, then attach disease evidence before program review.
Glucocorticoid receptor
Review this target as Glucocorticoid receptor, mapped to UniProt P06536. Sequence length is 795 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glucocorticoid receptor as ChEMBL target CHEMBL3368, mapped to UniProt P06536. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Glucocorticoid receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P06536 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glucocorticoid receptor |
| UniProt Accession | P06536 |
| Component Type | Protein |
| Sequence Length | 795 aa |
Glucocorticoid receptor
Review this target as Glucocorticoid receptor, mapped to UniProt P06536. Sequence length is 795 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3666814 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL1473 | 9.85 | IC50 | 0.14 | Approved |
| CHEMBL4072756 | 9.85 | IC50 | 0.14 | Clinical |
| CHEMBL4863316 | 9.8 | IC50 | 0.1585 | Preclinical |
| CHEMBL191423 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL433586 | 9.7 | EC50 | 0.2 | Preclinical |
| CHEMBL4877227 | 9.7 | IC50 | 0.1995 | Preclinical |
| CHEMBL312627 | 9.6 | IC50 | 0.2512 | Preclinical |
| CHEMBL3666813 | 9.54 | IC50 | 0.29 | Preclinical |
| CHEMBL3666807 | 9.52 | IC50 | 0.3 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 40 | 80 | 7.2 |
| single protein format | 33 | 50 | 7.5 |
| assay format | 20 | 14 | 7.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 43 | 0 | — |
| cell-based format | 14 | 29 | 7.7 |
| assay format | 9 | 7 | 7.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 35 | 7.2 |