Beta-1 adrenergic receptor · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P34971. Use UniProt P34971 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P34971 as the stable identity anchor, then attach disease evidence before program review.
Beta-1 adrenergic receptor
Review this target as Beta-1 adrenergic receptor, mapped to UniProt P34971. Sequence length is 466 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-1 adrenergic receptor as ChEMBL target CHEMBL3440, mapped to UniProt P34971. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Beta-1 adrenergic receptor is the right protein anchor across sources, using UniProt P34971 as the stable mapping.
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| Preferred Name | Beta-1 adrenergic receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P34971 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-1 adrenergic receptor |
| UniProt Accession | P34971 |
| Component Type | Protein |
| Sequence Length | 466 aa |
Beta-1 adrenergic receptor
Review this target as Beta-1 adrenergic receptor, mapped to UniProt P34971. Sequence length is 466 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL324665 | 10.05 | Ki | 0.09 | Clinical |
| CHEMBL3799125 | 9.68 | Ki | 0.21 | Preclinical |
| CHEMBL4537221 | 9.31 | Ki | 0.49 | Preclinical |
| CHEMBL4456301 | 8.96 | Ki | 1.1 | Preclinical |
| CHEMBL280822 | 8.85 | Ki | 1.4 | Preclinical |
| CHEMBL27 | 8.62 | Ki | 2.4 | Approved |
| CHEMBL4437569 | 8.59 | Ki | 2.6 | Preclinical |
| CHEMBL3798017 | 8.47 | Ki | 3.4 | Preclinical |
| CHEMBL3798748 | 8.29 | Ki | 5.1 | Preclinical |
| CHEMBL645 | 8.28 | Ki | 5.3 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 46 | 7.3 |