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Target Snapshot

CHEMBL612649 Target Snapshot

Trichophyton rubrum · ORGANISM · Trichophyton rubrum

Back to Search Search this target Browse approvals Evidence Card
2,830Compounds
324Assays
9Approved Drugs
69.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Trichophyton rubrum as ChEMBL target CHEMBL612649. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Trichophyton rubrum
ORGANISM · Trichophyton rubrum
As of 2026-09-13
ChEMBL target ID
CHEMBL612649
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Trichophyton rubrum still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameTrichophyton rubrum
Target TypeORGANISM
OrganismTrichophyton rubrum
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelTrichophyton rubrum
UniProt AccessionN/A

Trichophyton rubrum

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Trichophyton rubrum.

Review nameTrichophyton rubrum
OrganismTrichophyton rubrum
Clinical Profile

Clinical Phase Distribution

9
Approved
1
Phase II
Assay Mix

Activity Type Distribution

IC5069.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL157101 8.0 IC50 10.0 Approved
CHEMBL822 7.52 IC50 30.0 Approved
CHEMBL1630575 7.22 IC50 60.0 Approved
CHEMBL91 6.85 IC50 140.0 Approved
CHEMBL175633 6.72 IC50 190.0 Clinical
CHEMBL104 6.52 IC50 300.0 Approved
CHEMBL562 6.42 IC50 380.0 Approved
CHEMBL64391 6.25 IC50 560.0 Approved
CHEMBL267345 6.22 IC50 600.0 Approved
CHEMBL454322 6.22 IC50 600.0 Preclinical
Distribution

pChEMBL Value Distribution

8
5.0
16
5.5
14
6.0
3
6.5
2
7.0
2
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

CASPOFUNGIN
CHEMBL1630575
Approved 2001
Properties Compare Identifier
TERBINAFINE
CHEMBL822
Approved 1992
Properties Compare Identifier
ITRACONAZOLE
CHEMBL64391
Approved 1992
Properties Compare Identifier
KETOCONAZOLE
CHEMBL157101
Approved 1981
Properties Compare Identifier
CLOTRIMAZOLE
CHEMBL104
Approved 1975
Properties Compare Identifier
MICONAZOLE
CHEMBL91
Approved 1974
Properties Compare Identifier
AMPHOTERICIN B
CHEMBL267345
Approved 1964
Properties Compare Identifier
GRISEOFULVIN
CHEMBL562
Approved 1962
Properties Compare Identifier
Assay Landscape

Assay Landscape

324
Total Assays
36
Tested Compounds
1
Assay Types
Functional — 324 assays, 36 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 319 36 6.0
assay format 5 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine